During the 8th week of 2017, the Republic of Macedonia registered 227 influenza cases/flu-like diseases ( I=11,0/100.000). Compared with the registered cases in the last week  (220), the number has increased by 3.2%.

The total number of reported cases this week, exceed below the limit of low activity, according to MEM model to determine the intensity of the activity of seasonal flu (chart 1).

Chart 1. Intensity level and weekly distribution of influenza / influenza like illness, by the expected epidemic curve of 2010-2016, the season 2015/2016 and 2016/2017


The highest number of patients (n = 71) was registered on the territory of CPH Ohrid, then Gostivar-36, Tetovo-30. The highest incidence of 126.5/ 100,000, was registered on the territory of Ohrid, where was detected seasonal activity of the influenza virus, like in Debar(I=61,2/100.000). Also, a low seasonal activity was detected in 17 CPH/RO, and no cases in 12 CPH / RO. (chart 1)

Picture 1. Activity level of flu by the incidence of 100,000, week 8, 2017


This week, the highest number of patients (n = 175, 77.1%) have been reported in the largest age group of 15-64 years, children aged 5-14 with 7,5% (n=17), elderly 65+ with 11,5% (n=26), and children aged 0-4 with ((4,0%;  n=9). The highest incidence of  12.0/100,000 was registered in age group 15-64, in elderly (65+)  (I=9.9/100.000), , in children aged  0-4, I=7,8/100 0000,  and the lowest is registered in children aged 5-14 (7.3/100 000) (Chart 2).  

Chart 2. Distribution of seasonal flu by age groups and incidence per 100,000 inhabitants, season 2016/2017


The total number of flu cases is 34330 (I = 1659.1/ 100.000). This season have been reported infected people from all reporting units. The most of the cases which have been reported are from Skopje (n=4.555; 13,3%), Strumica (n=3.233; 9,4%), Gostivar (n=2.984; 8,7%), Kavadarci (n=2.976; 8,7%) and Bitola (n=2.826; 8,2%) (chart 3)

The highest incidence is registered on the territory of Kavadarci -(I=6915.5/100.000), Sveti Nikole- (I=5747.9/100.000), and Strumica (I=3413.3/100.000) (Chart 3). During this season were registered 2 deaths associated with influenza,

Chart 3. Distribution of seasonal flu by CPH/RO and incidence per 100,000 inhabitants, season 2016/2017



From the total number of cases of flu/flu-like illnesses, 17158 or 50.0% were reported in January, December 15073 or 43.9%,  1.5%(532) in November and 0.5%.(171) in October. 17158, or 50.3% are reported in January, 1396 or 4.1% in February.

Regarding the distribution of patients by age groups, the largest number of cases this season have been reported in the age group of 15-64 years –n=23666 or 68.9% and the highest incidence (1972.3 / 100,000, n=4565) is registered in the age groups 5-14 and in the age group of 0-4. (1918.4/100.000, n=2229). 3870 cases and incidence of (1476.3 / 100,000) is registered in the age group over 65. (Chart 4)

Chart 4. Distribution of seasonal flu by age groups, season 2016/2017



During the week 8 of 2017, the laboratory for virology of IPH has received  4 samples, (material for laboratory diagnostics), all negative to the presence of the influenza virus.

Since the beginning of the season 2016/2017, the laboratory received 159 materials, from the routine and sentinel and 58 (36.5%)  were positive for the presence of influenza virus, of which 55- Influenza A/H3, 2 non-typed Influenza A virus, 1 Influenza B. (chart 5)

Chart 5. Weekly distribution of number and percentage of positive samples of influenza 2016/2017


According to reports received by CPH / RO, 99.9% of total purchased vaccines are used, or 26665 persons are vaccinated.. The majority of the vaccinated are aged over 64 years – 15324 cases or 57.5%, 30-64 years – 10001 cases or 37,5%, and  5-29 – 661 cases or 2.5%. In the age group 0-4 years- 10 cases, and 613 health workers (2,3%). There are no vaccinated pregnant women. From the total number of the vaccinated, 17908 persons or 67.2% have a history of chronic diseases. The vaccination has finished in every CPH/RO



According to records presented in Flu News Europe (week 7/2017), the activity of influenza virus in Europe is with high activity, and the countries reported detection of 36% positive samples. The pandemic reached its peak in week 46 in the season 2009/2010, and week 48-51, in the previous 5 seasons. So far, this year, most of the viruses are subtyped as A (H3N2) with 99%, while last year, the subtype A(H1N1)pdm09 was predominant