During the 12th week of 2018 (19.03.2018 – 25.03.2018), the Republic of Macedonia registered 693  influenza cases/flu-like diseases(I=33.5/100.000).

Compared with the number of registered cases in the last week, are decreased for 47%(chart 1)and increased for 10 times compared with the cases of the last season.

Chart 1. Distribution of cases of seasonal influenza by week, typical epidemic curve of the seasons 2010-2017, 2016/2017 and 2017/2018

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Regarding the distribution of patients by age groups, the largest number of cases this week have been reported in the age group of 15-64 years (466 cases) and the highest incidence is registered in the age group, from 0-4 years. (I=45.6/100.000)

This week the biggest number of influenza cases is registered in Strumica, n= 131 and also, the highest incidence is registered in Sveti Nikole (I = 292,5/ 100.000).

From 31 reporting units, Sveti Nikole registered medium activity of the influenza virus, other units- registered low to very low activity,4 units didn’t registered any cases

Chart 2. Level of influenza activity according to the incidence of 100,000 inhabitants, week 12 2018

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In the 2017/2018 season, the total number of influenza like illness (ILI) cases is 23097 (I = 1116.2/ 100.000).Compared with the previous season (34725 cases), the number has decreased for 34%.

This season the biggest number of influenza cases is registered in Gostivar-2303, Skopje-3050, Strumica-2234, with the highest incindence in Kavadarci (I=3678.5 /100 000).

Regarding the distribution of patients by age groups, the largest number of cases this season have been reported in the age group of 15-64 years, 14051 cases (60.8%) and the highest incidence is registered in the age group of 5-14 years. (I=2019.4/100 000).

The analysis of the number of seasonal flu cases per month indicates a gradual increase in the number of patients in January (2,396 patients or 10.4%) and a peak in February (12,951 or 56.1%). In march, are registered 6668 or 28.9%

During this week the laboratory for virology of IPH has received 12 samples, materials for laboratory diagnostics. 6 samples(50%) are positive for the presence of influenza virus, subtyped as 66.7% Influenza B (75% Yamagata, 25% Victoria) and 33.3% Influenza A (of which 100% are A(H1N1)pdm09 (chart 2)

Since the beginning of the season 2017/2018, the laboratory received 451 materials, of which, 235 are positive (52.1%) for the presence of the influenza virus, 69.4% are Influenza B (89.9% Yamagata, 4.9% Victoria and 5.5% non-subtyped), and 30.6% are Influenza A of which (80.6% are А(H1N1)pdm09 –and 20% Influenza A non-subtyped),

Chart 2. Weekly distribution of number and percentage of positive samples of influenza 2017/2018

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According to reports received by CPH / RO, 27997 people were vaccinated, or 100% of total purchased vaccines. The majority of the vaccinated are aged over 65 years – 60.5%, From the total number of the vaccinated  75.2% have a history of chronic diseases.

EUROPE

According to records presented in Flu News Europe, the activity of influenza virus in Europe is widespread, The situation is common for this time of year.

This week, 44% samples were confirmed as positive, with the common circulation of Influenza A and Influenza B virus although most of the laboratory confirmed viruses belong to Influenza B.  B / Yamagata type is dominated by the registered Influenza B viruses, but this type is not included in the trivalent vaccine for this season.

Based on the data provided to EuroMOMO, mortality has increased over the past weeks, in some countries, and decreased in others